Dr Angela Stokes

About

Angela joined the Global and Lifelong Learning science academic
team full time in April 2022. She has a variety of teaching experiences,
ranging from adult education biology classes, to supervising student research
projects, lecturing and distance/blended learning. Angela is the co-chair of
the Science Apprentice Student Voice, supporting apprentices to feedback to the
department on their experiences.
Angela’s research interests focused on the use of DNA and
gene expression to predict and describe aspects of head and neck cancers, such
as grading, progression and treatment responses. She has a PhD in cancer
research, cell biology and genetics from the University of East Anglia
(Biomedical Research Centre), where her research focused on the ‘degradome’ –
proteases and their inhibitors – of head and neck squamous cell carcinoma
(HNSCC) and chemosensitivity testing. Her postdoctoral research at the King’s College
London Dental Institute focused on whole genome testing to predict malignant
transformation in longitudinal pre-malignant head and neck lesions, HPV
detection in oral and pharyngeal cancers, and the identification and modulation
of treatment responses in HNSCCs and cell lines by microRNAs. Angela also
worked in the Genome Analysis Centre (now the Earlham Institute) in Norwich and
the Lung Research Group at the University of Bristol. She was previously a
grants reviewer and independent scientific advisor for The Big C cancer charity.
Finally, Angela has over 10 years of experience as an academic editor.
 Publications include:
DNA aneuploidy and tissue architecture in oral potentially
malignant disorders with epithelial dysplasia assessed by 10 locus FISH panel.
Zaini Z, Neat M, Stokes A, Tavassoli M, Odell E. Oncology Rep. 2020,
43(3): 877-885.
Patients with HPV-related tonsil squamous cell carcinoma
rarely harbour oncogenic HPV infection at other pharyngeal sites. Thavaraj S,
Stokes A, Mazuno K, Henley-Smith R, Suh Y, Paleri V, Tavassoli M, Odell E,
Robinson M. Oral Oncol. 2014, 50(4): 241–6.
Human papillomavirus detection in dysplastic and malignant
oral verrucous lesions. Stokes A, Guerra E, Bible J, Halligan E, Orchard G,
Odell E, Thavaraj S. J Clin Pathol. 2012, 65(3): 283–6.
CD44 expression in oro-pharyngeal carcinoma tissues and cell
lines. Rajarajan A, Stokes A, Bloor B, Ceder R, Desai H, Grafström R, Odell E. PLoS
ONE. 2012, 7(1): e28776.
mRNA profiling of the cancer degradome in oesophago-gastric
adenocarcinoma. Baren JP, Stewart GD, Stokes A, Gray K, Pennington CJ, O’Neill
R, Deans DA, Paterson-Brown S, Riddick AC, Edwards DR, Fearon KC, Ross JA,
Skipworth RJ. Br J Cancer. 2012, 107(1): 143-9.
Copy number and loss of heterozygosity detected by SNP array
of formalin-fixed tissues using whole-genome amplification. Stokes A, Drozdov
I, Guerra E, Ouzounis C, Warnakulasuriya S, Gleeson M, McGurk M, Tavassoli M,
Odell E. PLoS ONE. 2011, 6(9): e24503. 
Evaluation of human papillomavirus testing for squamous cell
carcinoma of the tonsil in clinical practice. Thavaraj S, Stokes A, Guerra E,
Bible J, Halligan E, Long A, Okpokam A, Sloan P, Odell E, Robinson M. J Clin
Pathol. 2011, 64(4): 308–12.
Is head and neck cancer infectious? Human papilloma virus in
oral and pharyngeal cancer. Thavaraj S, Stokes A, Odell E. Faculty Dental
Journal. 2010, 1(3): 108–113.
Comment on "Oral Oncology editorial--Continued
misrepresentation of KB cells as being of oral cancer phenotype requires
action" [O'Neill ID. Oral Oncol. 2009, 45(10):e117–118]. Stokes A. Oral
Oncol. (2010), 46(5): e38. 
Expression profiles and clinical correlations of degradome
components in the tumor microenvironment of head and neck squamous cell
carcinoma. Stokes A, Joutsa J, Ala-Aho R, Pitchers M, Pennington C, Martin C,
Premachandra D, Okada Y, Peltonen J, Grénman R, James H, Edwards D, Kähäri V. Clin
Cancer Res. 2010,16(7): 2022–35. 
Variant CD44 expression by human fibroblasts. Rajarajan A,
Bloor B, Desai H, Stokes A, Odell E. Biomarkers. 2008, 3: 307–18.
Comment on "Aloe-emodin induces in vitro G2/M arrest
and alkaline phosphatase activation in human oral cancer KB cells" [Xiao
B, Guo J, Liu D, Zhang S. Oral Oncol. 2007, 43(9): 905–10]. Stokes A. Oral
Oncol. 2008, 44(6): 613.
Research tissue banking in ENT: Organization, methods, and
uses, with reference to practical, ethical and legal issues. Pitchers M, Stokes
A, Lonsdale R, Premachandra D, and Edwards D. JLO. 2006, 120: 433–438.
Stomatal responses to humic substances and auxin are
sensitive to inhibitors of phospholipase A. Russell L, Stokes A, Macdonald H,
Muscolo A, and Nardi S. Plant and Soil. 2006, 283: 175–185