Metabolism and Enzymology - LABS4080

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Module delivery information

Location Term Level1 Credits (ECTS)2 Current Convenor3 2024 to 2025
Medway
Year 4 15 (7.5) Carl Laxton checkmark-circle

Overview

A synopsis of the curriculum

• The characteristics of enzymes as biological catalysts, enzyme kinetics, enzyme classification
• The role of nucleic acids in synthesis of macromolecules, particularly proteins and enzymes
• Regulation of enzyme activity
• Anabolic and catabolic metabolic pathways
• Roles of ATP/NAD+/FAD
• Aerobic respiration, oxidative phosphorylation
• Products of glycolysis catabolism, anabolic formation of glucose, role of glycogen its formation and breakdown
• Fat metabolism and fat as an energy store
• Photosynthesis and its role in uptake of carbon dioxide and primary production of carbohydrate
• Human metabolic diseases related to altered amino acid metabolism and protein structure
• Enzyme/drug interactions

Details

Contact hours

Blended distance learning:
Contact hours: 120 hours
Private Study Time: 30 hours
Total Learning Time: 150 hours
.

Method of assessment

Portfolio 30% - composed of 5 individual assignments where topics are applied to the workplace
Assignments 40% - 2 Assignments (20% each)
Exam - MCQ – 30%
The pass mark for each individual assessment is 40%. All assessments must be passed in order to pass the module

Indicative reading

Price & Stevens, Fundamentals of Enzymology, Oxford University Press, USA, 2001.

Nelson & Cox, Lehninger Principles of Biochemistry, WH Freeman, New York, 2009.

Garrett, R.H., and Grisham, C.M., Principles of Biochemistry with a Human Focus, Brookes/Cole, USA, 2002.

See the library reading list for this module (Medway)

Learning outcomes

The intended subject specific learning outcomes.
On successfully completing the module students will be able to:
Describe basic metabolic pathways (anabolic and catabolic).
Demonstrate a knowledge and understanding of the role of energy conversions in cell metabolism.
Appreciate the role of nucleic acids and the genetic code in the synthesis of macromolecules.
Discuss human metabolic disorders related to altered amino acid metabolism.
Describe drug-enzyme interactions.
Link the above knowledge to everyday activities in the bioscience workplace.
The intended generic learning outcomes.
On successfully completing the module students will be able to:

Demonstrate the development of practical/technical skills.
Analyse, evaluate and correctly interpret data.
Communicate and present data effectively.
Obtain and use information from a variety of sources as part of self-directed learning.
Manage their time and use their organisation skills within the context of self-directed learning.

Notes

  1. Credit level 4. Certificate level module usually taken in the first stage of an undergraduate degree.
  2. ECTS credits are recognised throughout the EU and allow you to transfer credit easily from one university to another.
  3. The named convenor is the convenor for the current academic session.
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