Dr Mohinder Pal

Dr Mohinder Pal obtained an undergraduate degree in Medical Sciences at Punjab University, India, followed by a Master of Research degree in Biomedical Sciences at the University of Glasgow, Scotland. 

To gain structural biology expertise, he obtained a PhD degree in Biochemistry (X-ray crystallography) in Professor Steve Wood’s laboratory at the University of Southampton, UK. 

During his doctorate, he worked on drug discovery projects and determined several crystal structures of amyloidosis-related proteins such as Serum amyloid p component (SAP) and Transthyretin (TTR) using X-ray crystallography. 

He then joined the laboratory of Professor Laurence Pearl FRS as a Postdoctoral Research Fellow at the University of Sussex, Brighton, where his research focused on the structural studies of the HSP90 and R2TP (RUVBL1-RUVBL2-Tah1p/RPAP3-PIH1D1) molecular chaperones using X-ray crystallography and single particle cryo-electron microscopy (cryo-EM).

Mohinder’s research interests reside in discerning the roles of molecular chaperones in the assembly and regulation of multi-protein complexes. He is particularly interested in how the HSP90 and R2TP chaperone system recognises and assembles massive molecular machines involved in transcription and DNA repair processes. Additionally, he utilises his structural work as a platform to design small molecule inhibitors aimed at treating cancer and other diseases.

Proteins: Structure and Function  (BIOS6290)

Metabolism, Nutrition and Disease (BIOS5200)

Skills for Bioscientists 2 (BIOS5300)

My group is always open to Master of Research and PhD students who want to learn structural biology (X-ray crystallography and Single Particle Cryo-Electron Microscopy) complemented with other biochemistry and biophysical techniques. If you are enthusiastic about joining our research group and exploring these fields, please feel free to contact me at M.Pal@kent.ac.uk.

Member of the British Crystallographic Association.